MB-105 study (NCT06534060), a Phase 2, open-label, single-arm, multicenter clinical trial for patients with CD5-positive relapsed or refractory T-cell lymphoma (r/r TCL). The study uses a Simon two-stage design.
This trial is specifically for TCL Patients
There is an ongoing Phase 1 clinical trial (NCT03081910) for the autologous CD5 CAR-T, developed at Baylor College of Medicine, for T-cell lymphoma and T-cell acute lymphoblastic leukemia (TCL and T-ALL). Enrollment for this trial is ongoing and available to patients via a referring physician.
ClinicalTrials.gov ID NCT03081910
The Phase 1 trial (NCT03081910) at BCM continues to enroll patients with T-cell acute lymphoblastic leukemia (T-ALL) through physician referrals.
Enrollment for this trial will remain available for T-ALL patients.